Background and Objectives: Nowadays, obesity is recalled as a major problem among the people. The aim of the present research is to investigate the effects of supplementation of green tea and eight weeks of aerobic exercise on galanin serum levels and lipid profile of obese and non-athlete women.

Materials and Methods: This quasi-experimental research involves 32 women (age: 32/62 ± 6/8 years, height: 160/1 ± 0/6 cm, weight: 82/8 ± 1/1, BMI 32/2 ± 2) divided into four groups of eight members. The first group consists of green tea and exercise, the second group is green tea and without exercise, the third group is practiced without green tea, and the fourth group is the control. The bloody samples data was collected after 12-hour fasting, at 8am in the morning. Statistical analysis of the data was carried out using the SPSS software (version 21), one-way ANOVA and post hoc LSD tests at the significant level of P&le0/05.

Results: Serum galanin was decreased significantly in the first group compared with the control group, and the only difference between the second and third groups was statistically significant (P&le0/05). Total cholesterol and LDL-C was significantly decreased in the first and second groups compared with the control group (P&le0/05) but there was no significant difference between the groups regarding the changes in both factors (P&ge0/05). Changes in TG and HDL-C were not significant in any of the groups (P&ge0/05).

Conclusion: Green tea can be individually consumed to help reduce the total cholesterol level however, if it is combined with aerobic exercise, it can have positive effects and, at the same time, reduce low-density lipoprotein and serum levels of galanin.