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:: Volume 9, Issue 2 (Summer 2014) ::
Iranian J Nutr Sci Food Technol 2014, 9(2): 67-74 Back to browse issues page
Comparing analgesic effects of extra virgin olive oil and Ibuprofen on the intensity of primary dysmenorrhea: A crossover clinical trial
Maryam Rezaeyan * , Narges Abdali , Marzieh Araban
, Faculty member of Islamic Azad University, Borujerd branch, Midwifery department, Borujerd, Iran
Abstract:   (12035 Views)
Background and objective: Primary dysmenorrhea is a common problem among women in the child-bearing age. This study was designed to compare the analgesic effects of extra virgin olive oil and Ibuprofen in primary dysmenorrhea. Materials and methods: In a crossover randomized controlled trial (IRCT2013051110804N2), 60 university girl students (17-30 years old) in Boroojerd Islamic Azad University dormitory with the diagnosis of primary dysmenorrhea were enrolled based the CONSORT guidelines and divided randomly into 2 groups receiving either extra virgin olive oil (Group 1) or Ibuprofen (Group 2). Screening for primary dysmenorrhea was done by a visual analog scale. The participants were followed up for 4 menstruation cycles. The subjects in Group 1 took 25 cc of extra virgin olive oil daily for 2 months (starting two weeks before the start of the menstruation cycle) and completed a questionnaire containing items on pain visual analogue scale for two consecutive cycles. After a 4-week washout period they received 400 mg Ibuprofen three times a day in the first 3 days of menstruation. Group 2 was treated basically similarly, except that they received Ibuprofen during the first cycle and extra virgin olive oil during the second cycle. A self-reported checklist was used to collect information on menstruation. Data were analyzed using the Student's t-test and the linear mixed method model (SPSS 16). Results: Although before the intervention, both groups were similar (P > 0.05) in terms of demographic variables and the outcome measures, the results showed that there were significant differences in the severity of pain during the pre- and post-treatment periods between the Ibuprofen and extra virgin oil groups (P=0.001). In addition, the severity of pain was less in the extra virgin olive oil as compared to the Ibuprofen group. Conclusion: Extra virgin olive oil is effective in treating primary dysmenorrhea and it seems that it can be used as a substitute for nonsteroidal anti-inflammatory drugs. Keywords: Primary dysmenorrhea, Extra virgin olive oil, Ibuprofen, Crossover clinical trial
Keywords: Primary dysmenorrhea, Extra virgin olive oil, Ibuprofen, Crossover clinical trial
Full-Text [PDF 215 kb]   (1937 Downloads)    
Article type: Research | Subject: nutrition
Received: 2013/09/18 | Accepted: 2014/05/5 | Published: 2014/07/27
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Rezaeyan M, Abdali N, Araban M. Comparing analgesic effects of extra virgin olive oil and Ibuprofen on the intensity of primary dysmenorrhea: A crossover clinical trial. Iranian J Nutr Sci Food Technol 2014; 9 (2) :67-74
URL: http://nsft.sbmu.ac.ir/article-1-1293-en.html


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Volume 9, Issue 2 (Summer 2014) Back to browse issues page
Iranian Journal of  Nutrition Sciences and Food  Technology
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