| this is a test
|
|
 |
Search published articles |
 |
|
Showing 4 results for Rakhsha
A Milajerdi, Sh Akhonzadeh, Sh Jazayeri, E Shirzadi, N Hashemzadeh, Zh Derakhshan, A Djazayeri, M Mahmoodi,
Volume 11, Issue 3 (Autumn 2016)
Abstract
Background and Objectives: Depression and anxiety are the major public health problems worldwide, which may act synergistically. Type 2 diabetes can cause and aggravate mental disorders such as depression and anxiety. Saffron as a medicinal plant may attenuate mixed depression and anxiety (MDA).
Materials & Methods: A total of 54 outpatients with mild to moderate MDA diagnosed by Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV) were assessed by Beck and Hamilton’s depression and anxiety questionnaires. The patients, in this randomized triple-blind placebo-controlled clinical trial, randomly received 15 mg saffron extract or placebo capsules twice a day for 8 weeks.
Results: After the intervention, depression, anxiety and MDA were significantly (P<0.05) attenuated in the saffron group (18, 30 and 25% in Beck and 19, 36 and 24% in the Hamilton measures, respectively), while changes in the placebo group were not significant. In addition, dietary intakes and physical activity of the patients of the two groups did not change significantly during the intervention.
Conclusion: The study results suggest that saffron shows attenuating effect on mild to moderate MDA in patients with type 2 diabetes.
Keywords: Crocus Sativus L., Mixed depression-anxiety, Saffron, Type 2 Diabetes
1.Salehi L, Selki S, Alizadeh L. Evaluation of health-related quality of life of elderly members aged care center in Tehran in 2009. Iranian Journal of Epidemiology 2012;8(1):14-20. 2.Minichiello V, Coulson I. Contemporary issues in gerontology:promoting positive aging. Crows Nest, N.S.W: Allen & Unwin; 2005. 3.Blake G.J, Ridker P.M. Inflammatory bio-marker and cardiovascular risk prediction: J Intern Med 2002;252 (4):283-94. 4.Bhatt DL, Steg PG, Ohman EM, Hirsch AT, Ikeda Y, Mas JL, et al. REACH Registry Investigators:International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosis. JAMA 2006; 295(2):180-89. 5.Nayebifar S, Afzalpour M, Saghebjoo M, Hedayati M, Shirzaee P. The effect of aerobic and resistance trainings on serum C- Reactive Protein, lipid profile and body composition in overweight women. J Birjand Univ Med Sci 2012;8(4):186-96.[in Persian] 6.Mogharnasi M, Gaeini A, Sheikholeslami Vatani D. Comparing the effects of two training methods of aerobic and anaerobic on some pre-inflammatory cytokines in adult male rats. Iran J Endocrinol Metab 2010;11(2):191-98.[in Persian] 7.Wilund KR. Is the anti-inflammatory effect of regular exercise responsible for reduced cardiovascular disease? Clin Sci (Lond) 2007;112(11):543-55. 8.Anderson GP. Chronic Obstructive Pulmonary Disease, asthma and C-reactive protein. Eur Respir J 2006;27(5):874-6. 9.Pakzad Pervez. Serologic and Clinical Principles of interpretation. Tehran: Noore Danesh; 1392.[in Persian] 10.Esmaillzadeh A, Kimiagar M, Mehrabi Y, Azadbakht L, Hu FB, Willett WC. Fruit and vegetable intakes, C-reactive protein, and the metabolic syndrome. Am J Clin Nutr 2006 Dec;84(6):1489-97. 11.Khalil Hosseini, Nick Varz Naemeh, Eliasi Sepideh. Drug Treatment Of Diseases Of The Elderly. Tehran: Arjmand; 1392.[in Persian] 12.Spittle MA, Hoenich NA, Handelman GJ, Adhikarla R, Homel P, Levin NW. Oxidative stress and inflammation in hemodialysis patients. Am J Kidney Dis2001;38:1408-73. 13.Fung TT, McCullough ML, Newby PK, Manson JE, Meigs JB, Rifai N, et al. Diet-quality scores and plasma concentrations of markers of inflammation and endothelial dysfunction. Am J Clin Nutr 2005 Jul;82(1):163-73. 14. Esmaillzadeh A, Azadbakht L. Association consumption of fruits and vegetables with plasma CRP levels and the prevalence of metabolic syndrome in women. Iranian Journal of Diabetes and Lipid 1386; 6 (3): 271-83.[in Persian] 15.Ahra K, Hyesook K, Chan-Jung H, Ji-Myung K, Hye-Won C, Namsoo C. Association between high sensitivity C-reactive protein and dietary intake in Vietnamese young women. Nutrition Research and Practice. 2014;8(4):445-52. 16.Ghaffarpour M, Hoshyarrad A, Kianfar H.Guidlines of home measurement, conversation coefficient and percent of edible of foods.Tehran: Agriculture Science Publisher; 1999.[in Persian] 17.Esfahani FH, Asghari G, Mirmiran P, Azizi F.Reproducibility and relative validity of food groupintake in a food frequency questionnaire developed for the Tehran Lipid and Glucose Study. J Epidemiol. 2010; 20(2): 150-8.[in Persian] 18.Malekshah AF, Kimiagar M, Saadatian-Elahi M, Pourshams A, Nouraie M, Goglani G, et al. Validity and reliability of a new food frequency questionnaire compared to 24 h recalls and biochemical measurements: pilot phase of Golestan cohort study of esophageal cancer. Eur J Clin Nutr 2006;60(8):971-77.[in Persian] 19.Fredrikson GN, Hedblad B, Nilsson JA, Alm R, Berglund G, Nilsson J. Association between diet, lifestyle, metabolic cardiovascular risk factors, and plasma C-reactive protein levels. Metabolism 2004;53:1436-42. 20.Paknahad Z, Heidari beni M, Shaygan Nejhad V. Association between dietary fats with lipid profiles and CRP level in Multiple Sclerosis women patients. Journal of Health System Research 1392; 1434-41.[in Persian] 21.Tannock LR, Kevin DO, Robert HK, Barbara R, Brian F, Mark HW, et al. Cholesterol Feeding Increases C-Reactive Protein and Serum Amyloid A Levels in Lean Insulin-Sensitive Subjects. Circulation. 2005;111:3058-62. 22.Esmaillzadeh A, Kimiagar M, Mehrabi Y, Azadbakht L, Frank B Hu, Walter CW. Dietary Patterns and Markers of Systemic Inflammation among Iranian Women. J Nutr 2007;137:992–8. 23.King DE, Egan BM, Woolson RF. Effect of a highfiber diet vs a fiber supplemented diet on C-reactive protein level. Arch Intern Med 2007; 167(5): 502-6. 24. Kafeshani O, Entezari M, Hoseini M, Mohebrasool M, Sohrabi F, Torabi A. Correlation of inflammatory and nutrients intake in Isfahan hemodialysis patients. Journal of Health System Research 1389; 6(2): 344-50.[in Persian] 25. Taghdir M, Ashourpour M, Ghandchi Z, Pourghaderi M, Sepandi M, Alavi Naini. Assessment of Energy and Protein Intake and Some of the Related Factors in Hemodialysis Patients Referred to ImammKhomeini Hospital. Iranian Journal of Endocrinology and Metabolism 1390; 13(6): 690-96.[in Persian] 26.Santos FL, Esteves SS, da Costa Pereira A, Yancy WS Jr, Nunes JP. Systematic review and meta-analysis of clinical trials of the effects of low carbohydrate diets on cardiovascular risk factors. Obes Rev 2012;13(11):1048-66. 27.Due A, Toubro S, Stender S, Skov AR, Astrup A. The effect of diets high in protein or carbohydrate on inflammatory markers in overweight subjects. Diabetes Obes Metab 2005; 7:223-9. 28.Mohammad shahi M, Heidari F, Moula K, Helli B, Ijadi M, Amirian Z, et al. Association of Dietary Patterns and Indicators of Disease Activity in Patients with Rheumatoid Arthritis. Iranian Journal of Nutrition Sciences & Food Technology 1393; 9(3): 9-20.[in Persian] 29.Pahlavani N, Sadeghi O, Rasad H, Azizi soleiman F. The Relationship between Inflammation, Oxidative Stress, Blood Sugar, Blood Lipid, Body Mass Index, Fat Mass, and Body Weight in Patients with Type 2 Diabetes. Journal of Diabetes Nursing and Midwifery Zabol 1393; 2(2): 42-51.[in Persian] 30.Bertran N, Camps J, Fernandez-Ballart J, Arija V, Ferre N, Tous M, et al. Diet and lifestyle are associated with serum C-reactive protein concentrations in a population-based study. J Lab Clin Med 2005;145(1):41-6
Z Aarchahi, A Kooshki, Mh Rakhshani, T Tofighiyan,
Volume 12, Issue 2 (Summer 2017)
Abstract
Background and Objectives: High-Sensitivity C-reactive protein (hs-CRP) is the most reliable means of diagnosing and controlling hidden inflammation and infection in the body. poor nutritional status in older adults with increased serum levels of CRP, followed by systemic inflammation is linked. It appears that diet has an significant effect on chronic inflammation affecting the progression of the disease. This study aimed to examine the association between macronutrients intake with serum High sensitivity C-reactive protein in elderly located in nursing homes in Sabzevar.
Materials & Methods: This cross-sectional analytical study included 105 nursing home residents from Sabzevar city, stratified sampling method was performed. Anthropometric indexes, BMI and WHR were measuremed according standard methods. Nutrientional intake per person was collected and determined by using the N4 software. Blood samples were collected for measurement of serum hs-CRP. Data were analyzed by using SPSS software descriptive statistics and regression.
Results: In the present study, a significant positive correlation between total fat and cholesterol intake and a significant inverse correlation between fiber intake and serum high sensitivity C- reactive protein was observed. Among Anthropometric indexes, hs-CRP has a statistically significant relationship with BMI.
Conclusion: According to results of this study, diets high in fiber, low in fat, low cholesterol should be the first level of prevention in this age group and it can reduce inflammation remarkably.
Z Alboghobeish, Z Nazari, Z Sheikhi Mobarakeh, A Rakhsha, M Houshyari, E Hejazi,
Volume 16, Issue 4 (Winter 2022)
Abstract
Background and Objectives: Sleep disruption is a common side effect in breast cancer patients undergoing radiotherapy. Therefore, the aim of this study was to assess effects of tahini consumption on sleep quality in breast cancer patients undergoing radiotherapy.
Materials & Methods: Forty-eight women with breast cancer undergoing radiotherapy were randomly assigned to intervention and control groups. In the intervention group, daily tahini consumption included 48 g during the radiation therapy course (five weeks). Patients completed Pittsburg sleep quality index questionnaires in the baseline and after the finish of radiotherapy. Chi-square, t-test, Mann-Whitney, Wilcoxon and Binary logistic regression analyses were carried out.
Results: Mean (standard deviation) age of the participants was 47.97 y ±10.65. Moreover, 50% of the patients in tahini group and 80.8% of the patients in control group had poor sleep qualities (p = 0/02). Overall, tahini consumption significantly improved the total score of sleep quality, compared to the control group (p = 0/006). Moreover, significant differences were seen between the two groups in most subscales, including subjective sleep quality (p = 0/008), sleep latency (p = 0/01), sleep duration (p = 0/003) and sleep disturbances (p = 0/05). Moreover, the mean changes in the scale of sleep disturbances showed statistically significant differences between the two groups (p = 0.002). The intervention group had lower odds ratios for the subscales of subjective sleep quality (p = 0.01), sleep latency (p = 0.01), sleep duration (p = 0.006), sleep disturbances (p = 0.04) and total score of sleep quality (p = 0.007), compared to the control group.
Conclusion: These results have shown that tahini consumption during radiotherapy increases the quality of sleep in patients with breast cancer.
Z Nazari, Z Alboghobeish, E Hejazi, Z Sheikhi Mobarakeh, A Rakhsha, M Houshyari, Ar Bahrami,
Volume 17, Issue 1 (Spring 2022)
Abstract
Background and Objectives: Fatigue and sleep disturbance are side effects of radiation therapy. Grape juice is a traditional product rich in antioxidants and polyphenols that have been shown to include positive effects on improving fatigue and sleep disorders. The aim of this study was to assess effects of grape juice consumption on fatigue and sleep quality in women with breast cancer undergoing radiation therapy.
Materials & Methods: In this controlled clinical trial, 44 women with breast cancer aged 18–70 years were randomly divided into intervention and control groups. The intervention group consumed 100 g of grape juice daily from the beginning of treatment until five weeks and the control group did not consume any medications or placebo. Fatigue scores and sleep quality were assessed and compared between the two groups at the beginning and end of the study using fatigue questionnaires (MFSI-SF) and sleep quality questionnaires (PSQI). study using fatigue and sleep quality questionnaires(MFSI-SF, PSQI ). Data analysis was carried out using paired t-test and independent t-test.
Results: In this study, physical fatigue scales were significantly different between the two groups with the consumption of grape juice (p < 0.05), but the overall fatigue rates were not significant between the two groups (p ≥ 0.05). By examining the scores linked to sleep quality, it was shown that the sleep disorder scale of the intervention group significantly decreased, compared to the control group (p < 0.05). In the overall quality of sleep or PSQI, significant differences were not observed between the two groups (p ≥ 0.05).
Conclusion: Findings of the present study reveal that consumption of grape juice can decrease side effects of radiation therapy (physical fatigue and sleep disorders) in women with breast cancer.
|
|
