[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 9, Issue 2 (Summer 2014) ::
2014, 9(2): 19-27 Back to browse issues page
The effects of whole grain intake on the metabolic profile in obese girls: a crossover randomized clinical trial
P Hajihashemi, L Azadbakht, M Hashemipor, R Kelishadi, A Esmaillzadeh *
Abstract:   (6062 Views)
Background and objective: Although whole-grain foods have been reported to affect the metabolic profile, limited data are available in this regard on children. The present study aimed to determine the effects of whole-grain consumption on fasting blood glucose and lipid profile of overweight or obese children. Materials and methods: This randomized cross-over clinical trial included 44 overweight or obese (BMI>85th percentile for age and sex) girls aged 8-15 years. After a 2-week run-in period, the subjects were randomly assigned to either an intervention or a control group. The subjects in the intervention group were given a list of whole-grain foods (dark bread (sangak and barbari), brown rice, whole-meal biscuits, wheat germ, wheat bran and cornflakes) and asked to choose and consume 50% of their daily grain servings, for 6 weeks, from among whole-grain foods. Those in the control group were given similarly a list of whole-grain foods and asked not to consume any of those foods during the intervention phase of the study. A 4-week washout period was applied following which the subjects were crossed over to the alternate arm for an additional 6 weeks. Fasting blood samples were taken before and after each phase of study for biochemical measurements and metabolic profile determination. Results: Mean (±SD) age, body mass index, systolic and diastolic blood pressures of the subjects were 11.2±1.49 years and 23.5±2.5 kg/m2, 111.4±9.7 and 66.4±9.1 mmHg, respectively. After 6 weeks we found significant effects of consuming whole-grain foods on plasma glucose (changes from baseline in the intervention group -1.9 vs. 3.8 mg/dL in the control group, P=0.01), serum triglycerides (changes from baseline in the intervention group -16 vs. 7 mg/dL in the control group, P=0.01), and serum HDL-cholesterol levels (changes from baseline in the intervention group 6.3 vs. -5.6 mg/dL in the control group, P=0.05) . Whole grain intake had no significant effect on serum total and LDL-cholesterol concentrations or blood pressure. Conclusion: This study provides evidence supporting the beneficial effects of consuming whole-grain foods on the serum levels of fasting blood glucose and lipid profile (TG and HDL) in obese or overweight children. Keywords: Whole grains, Metabolic profile, Obesity, Overweight, Girls
Keywords: Whole grains, Metabolic profile, Obesity, Overweight, Girls
Full-Text [PDF 216 kb]   (1540 Downloads)    
Type of Study: Research | Subject: nutrition
Received: 2013/10/8 | Accepted: 2014/07/27 | Published: 2014/07/27
Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Hajihashemi P, Azadbakht L, Hashemipor M, Kelishadi R, Esmaillzadeh A. The effects of whole grain intake on the metabolic profile in obese girls: a crossover randomized clinical trial. Iranian Journal of Nutrition Sciences & Food Technology. 2014; 9 (2) :19-27
URL: http://nsft.sbmu.ac.ir/article-1-1317-en.html


Volume 9, Issue 2 (Summer 2014) Back to browse issues page
Iranian Journal of  Nutrition Sciences & Food  Technology
Persian site map - English site map - Created in 0.05 seconds with 32 queries by YEKTAWEB 4071