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The Impact of Vitamins and/or Mineral Supplementation on Blood Pressure in
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M Farvid *   , M Jalali , F Siassi |
| , farvidm@hotmail.com |
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Abstract: (15517 Views) |
| Objective: The present study designed to assess the effect of Mg+Zn, vitamin C+E, and combination of these micronutrients on blood pressure in type 2 diabetic patients.
Materials and Methods: In a randomized, double-blind, placebo controlled clinical trial, 69 type 2 diabetic patients were randomly divided into four groups. Each group receiving one of the following daily supplement for 3 months group M: 200 mg Mg and 30 mg Zn (n=16), group V: 200 mg vitamin C and 150 mg vitamin E (n=18), group MV: minerals plus vitamins (n=17), group P: placebo (n=18). Blood pressure was measured at the beginning and at the end of the trial.
Results: Results indicate that after 3 months of supplementation levels of systolic, diastolic and mean blood pressure decreased significantly in the MV group by 8 mmHg (122±16 vs. 130±19 mmHg), 6 mmHg (77±9 vs. 83±11 mmHg), and 7 mmHg (92±9 vs. 99±13 mmHg), respectively (p<0.05). Combination of vitamin and mineral supplementation had significantly effects in increasing serum potassium and sodium to potassium ratio (p<0.05). There was no significant change in the levels of these parameters in the other 3 groups. Also serum malondialdehyde decreased significantly in group M and MV (p<0.05 and p<0.01, respectively).
Conclusion: The results of the present study indicated that in type 2 diabetic patients, combination of vitamins and minerals rather than vitamin C and E, or Mg and Zn, might decrease blood pressure. |
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| Keywords: Type 2 diabetes, Vitamin C, Vitamin E, Magnesium, Zinc, Blood pressure |
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Full-Text [PDF 292 kb]
(2878 Downloads)
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Article type: Research |
Subject:
Food Science
Received: 2008/06/28 | Published: 2006/09/15
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