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Home use of vegetable oils, markers of systemic inflammation and endothelial dysfunction among women
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F Zaribaf   , F Haghighatdoost , L Azadbakht , A Esmaillzadeh * |
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Abstract: (16882 Views) |
| Background and Objective: Most of the information on the adverse health effects of trans fats has been mainly obtained from studies done in western populations very little information is available in this area from the Middle-East. The objective of this study was to determine the association between consumption of partially hydrogenated vegetable oils (PHVOs) and non-HVOs and circulating levels of inflammatory markers among Tehrani female-teachers 40-60 years old.
Materials and Methods: Usual dietary intakes of 486 apparently healthy women were assessed using a semi-quantitative food frequency questionnaire. The vegetable oils consumed were catagorized into PHVOs (commonly used for cooking in Iran) and non-HVOs (sunflower, corn, canola, soybeanm., and olive oils) Anthropometric measurements were made and fasting blood samples were taken for measuring inflammatory markers.
Results: The energy-adjusted daily intakes of PHVOs and non-HVOs were 23±11 and 22±10 g/d, respectively. After controlling for potential confounders, the plasma levels of CRP, TNF-α, IL-6, and soluble intercellular adhesion molecules (sICAM-1) of the women in the top quintile of PHVOs intake (as compared to the lowest quintile) were 45% (Ptrend< 0.01), 66% (Ptrend< 0.1), 72% (Ptrend< 0.05), and 22%( Ptrend<0.01), respectively. In contrast, a higher consumption of non-HVOs was associated with lower circulating levels of CRP (-23%, Ptrend=0.05), TNF-α (-29%, Ptrend<0.01), SAA (-24%, Ptrend<0.01), and soluble intercellular adhesion molecule ICAM-1 (-19%, Ptrend<0.05) when the top intake quantile was compared with the lowest . Adjustment for body mass index, fasting plasma glucose, and lipid profile slightly attenuated the associations in some cases.
Conclusion: Higher intakes of PHVOs are associated with elevated levels of inflammatory biomarkers, while higher intakes of non-HVOs are associated with lower plasma levels of these biomarkers in female-teachers.
Keywords: Partially hydrogenated vegetable oils, Inflammation, Trans fatty acids, Cardiovascular disease, Women |
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| Keywords: Partially hydrogenated vegetable oils, Inflammation, Trans fatty acids, Cardiovascular disease, Women |
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Full-Text [PDF 372 kb]
(2349 Downloads)
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Article type: Research |
Subject:
Food Science
Received: 2011/03/2 | Published: 2011/04/15
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