[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 16, Issue 1 (Spring 2021) ::
Iranian J Nutr Sci Food Technol 2021, 16(1): 75-84 Back to browse issues page
Application of Flat Electromembrane and Low-Density Solvent Extractions for the Assessment of Polar and Non-Polar Heterocyclic Aromatic Amines in Heated Red Meats
M Kamankesh * , A Mohammadi , F Barzegar, A Mollahosseini
Sabzevar university of medical sciences
Abstract:   (269 Views)
Background and Objectives: Heating, cooking and grilling of meat products form polar and non-polar heterocyclic aromatic amines as toxic compounds. The current study was carried out for the first time to assess polar and non-polar heterocyclic aromatic amines in grilled meats using two novel flat electromembrane and low-solvent microextraction and to compare these two techniques.
 Materials & Methods: In this study, two efficient methods of low-density solvent and flat electromembrane extractions were used for the sample preparation. Affecting factors in extraction of heterocyclic aromatic amines were separately optimized. Moreover, merit figures of the two methods were calculated and compared with each other.
Results: Value of each effecting factor in extraction were calculated for the two methods. Validation methods were carried out and results revealed high capability and validation of the two methods for the analysis of real samples. Recovery rates of higher than 90% for the two methods, detection limits of 0.2–1.7 and relative standard deviation of 3.5–8% verified use of the highlighted methods for real samples. Levels of heterocyclic aromatic amines were reported as not determined to 8 ng g-1.
Conclusion: Results of this study showed that the two microextraction methods included high sensitivity, accuracy and recovery to assess heterocyclic aromatic amines in meat products. Furthermore, volumes of the extraction solvents in the two techniques were small that were advantages of the suggested methods (green chemistry). In conclusion, the suggested methods include capabilities to assess heterocyclic aromatic amines in various heated red meat products.
Keywords: Heterocyclic aromatic amines, Heated red meat, Low-density solvent extraction, Flat electromembrane extraction, Reverse-phase liquid chromatography
Full-Text [PDF 792 kb]   (92 Downloads)    
English: Research | Subject: Food Science
Received: 2020/09/13 | Accepted: 2021/01/3 | Published: 2021/03/25
1. Mitra S. Sample preparation techniques in analytical chemistry: John Wiley & Sons; 2004. [DOI:10.1002/0471457817]
2. Chen Y, Guo Z, Wang X, Qiu C. Sample preparation. Journal of Chromatography A. 2008;1184(1-2):191-219. [DOI:10.1016/j.chroma.2007.10.026]
3. Kamankesh M, Mohammadi A, Hosseini H, Tehrani ZM. Rapid determination of polycyclic aromatic hydrocarbons in grilled meat using microwave-assisted extraction and dispersive liquid-liquid microextraction coupled to gas chromatography-mass spectrometry. Meat science. 2015;103:61-7. [DOI:10.1016/j.meatsci.2015.01.001]
4. Mohammadi A, Tavakoli R, Kamankesh M, Rashedi H, Attaran A, Delavar M. Enzyme-assisted extraction and ionic liquid-based dispersive liquid-liquid microextraction followed by high-performance liquid chromatography for determination of patulin in apple juice and method optimization using central composite design. Analytica chimica acta. 2013;804:104-10. [DOI:10.1016/j.aca.2013.09.045]
5. Makoś P, Słupek E, Gębicki J. Hydrophobic deep eutectic solvents in microextraction techniques-A review. Microchemical Journal. 2020;152:104384. [DOI:10.1016/j.microc.2019.104384]
6. Jalili V, Barkhordari A, Ghiasvand A. A comprehensive look at solid-phase microextraction technique: A review of reviews. Microchemical Journal. 2020;152:104319. [DOI:10.1016/j.microc.2019.104319]
7. Durak BY, Chormey DS, Firat M, Bakirdere S. Validation of ultrasonic-assisted switchable solvent liquid phase microextraction for trace determination of hormones and organochlorine pesticides by GC-MS and combination with QuEChERS. Food chemistry. 2020;305:125487. [DOI:10.1016/j.foodchem.2019.125487]
8. Napylov A, Reyes‐Garces N, Gomez‐Rios G, Olkowicz M, Lendor S, Monnin C, et al. In Vivo Solid‐Phase Microextraction for Sampling of Oxylipins in Brain of Awake, Moving Rats. Angewandte Chemie International Edition. 2020;59(6):2392-8. [DOI:10.1002/anie.201909430]
9. Jeleń HH, Majcher M, Dziadas M. Microextraction techniques in the analysis of food flavor compounds: A review. Analytica chimica acta. 2012;738:13-26. [DOI:10.1016/j.aca.2012.06.006]
10. Bordagaray A, Millán E, Garcia-Arrona R. A review on microextraction techniques for selected triazole fungicides determination in water and food samples. J Food Chem Nanotechnol. 2016;2(3):128-37. [DOI:10.17756/jfcn.2016-021]
11. Jalili V, Barkhordari A, Ghiasvand A. New extraction media in microextraction techniques. A review of reviews. Microchemical Journal. 2020;153:104386. [DOI:10.1016/j.microc.2019.104386]
12. Rezaee M, Assadi Y, Hosseini M-RM, Aghaee E, Ahmadi F, Berijani S. Determination of organic compounds in water using dispersive liquid-liquid microextraction. Journal of Chromatography A. 2006;1116(1-2):1-9. [DOI:10.1016/j.chroma.2006.03.007]
13. Rykowska I, Ziemblińska J, Nowak I. Modern approaches in dispersive liquid-liquid microextraction (DLLME) based on ionic liquids: A review. Journal of molecular liquids. 2018;259:319-39. [DOI:10.1016/j.molliq.2018.03.043]
14. Almeida C, Fernandes J, Cunha S. A novel dispersive liquid-liquid microextraction (DLLME) gas chromatography-mass spectrometry (GC-MS) method for the determination of eighteen biogenic amines in beer. Food Control. 2012;25(1):380-8. [DOI:10.1016/j.foodcont.2011.10.052]
15. Mashayekhi HA, Abroomand-Azar P, Saber-Tehrani M, Husain SW. Rapid determination of carbamazepine in human urine, plasma samples and water using DLLME followed by RP-LC. Chromatographia. 2010;71(5-6):517-21. [DOI:10.1365/s10337-009-1456-6]
16. Agus BAP, Hussain N, Selamat J. Quantification of PAH4 in roasted cocoa beans using QuEChERS and dispersive liquid-liquid micro-extraction (DLLME) coupled with HPLC-FLD. Food chemistry. 2020;303:125398. [DOI:10.1016/j.foodchem.2019.125398]
17. Pedersen-Bjergaard S, Rasmussen KE. Electrokinetic migration across artificial liquid membranes: new concept for rapid sample preparation of biological fluids. Journal of Chromatography A. 2006;1109(2):183-90. [DOI:10.1016/j.chroma.2006.01.025]
18. Maurice A, Theisen J, Gabriel J-CP. Microfluidic Lab-on-Chip Advances for Liquid-Liquid Extraction Process Studies. Current Opinion in Colloid & Interface Science. 2020. [DOI:10.1016/j.cocis.2020.03.001]
19. Mirasoli M, Guardigli M, Michelini E, Roda A. Recent advancements in chemical luminescence-based lab-on-chip and microfluidic platforms for bioanalysis. Journal of pharmaceutical and biomedical analysis. 2014;87:36-52. [DOI:10.1016/j.jpba.2013.07.008]
20. Sikanen T, Pedersen-Bjergaard S, Jensen H, Kostiainen R, Rasmussen KE, Kotiaho T. Implementation of droplet-membrane-droplet liquid-phase microextraction under stagnant conditions for lab-on-a-chip applications. Analytica chimica acta. 2010;658(2):133-40. [DOI:10.1016/j.aca.2009.11.002]
21. Maurice A, Theisen J, Gabriel J-CP. Microfluidic Lab-on-Chip Advances for Liquid-Liquid Extraction Process Studies. Current Opinion in Colloid & Interface Science. 2020. [DOI:10.1016/j.cocis.2020.03.001]
22. Alidoust M, Yamini Y, Baharfar M, Seidi S, Rasouli F. Microfluidic-enabled versatile hyphenation of electromembrane extraction and thin film solid phase microextraction. Talanta. 2020:121864. [DOI:10.1016/j.talanta.2020.121864]
23. Abdel-Rehim M, Pedersen-Bjergaard S, Abdel-Rehim A, Lucena R, Moein MM, Cárdenas S, et al. Microextraction approaches for bioanalytical applications: An overview. Journal of Chromatography A. 2020;1616:460790. [DOI:10.1016/j.chroma.2019.460790]
24. Delfino RJ, Sinha R, Smith C, West J, White E, Lin HJ, et al. Breast cancer, heterocyclic aromatic amines from meat and N-acetyltransferase 2 genotype. Carcinogenesis. 2000;21(4):607-15. [DOI:10.1093/carcin/21.4.607]
25. Sander A, Linseisen J, Rohrmann S. Intake of heterocyclic aromatic amines and the risk of prostate cancer in the EPIC-Heidelberg cohort. Cancer Causes & Control. 2011;22(1):109-14. [DOI:10.1007/s10552-010-9680-9]
26. Liao G, Xu X, Zhou G. Effects of cooked temperatures and addition of antioxidants on formation of heterocyclic aromatic amines in pork floss. Journal of food processing and preservation. 2009;33(2):159-75. [DOI:10.1111/j.1745-4549.2008.00239.x]
Send email to the article author

Add your comments about this article
Your username or Email:


XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Kamankesh M, Mohammadi A, Barzegar F, Mollahosseini A. Application of Flat Electromembrane and Low-Density Solvent Extractions for the Assessment of Polar and Non-Polar Heterocyclic Aromatic Amines in Heated Red Meats. Iranian J Nutr Sci Food Technol. 2021; 16 (1) :75-84
URL: http://nsft.sbmu.ac.ir/article-1-3130-en.html

Volume 16, Issue 1 (Spring 2021) Back to browse issues page
Iranian Journal of  Nutrition Sciences & Food  Technology
Persian site map - English site map - Created in 0.04 seconds with 30 queries by YEKTAWEB 4299